Network approaches for plant phylogenomic synteny analysis

Zhao, Tao; Schranz, Eric


<p>Network analysis approaches have been widely applied across disciplines. In biology, network analysis is now frequently adopted to organize proteinprotein interactions, organize pathways and/or to interpret gene co-expression patterns. However, comparative genomic analyses still largely rely on pairwise comparisons and linear visualizations between genomes. In this article, we discuss the challenges and prospects for establishing a generalized plant phylogenomic synteny network approach needed to interpret the wealth of new and emerging genomic data. We illustrate our approach with an example synteny network of B-class floral MADS-box genes. A broad synteny network approach holds great promise for understanding the evolutionary history of genes and genomes across broad phylogenetic groups and divergence times.</p>