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profile_subnav_projects - prof.dr. J (John) van der Oost
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‘CARFing’ out the signalling network of CRISPR-Cas
CRISPR are prokaryotic immune systems associated with nucleic acid degradation. Here, we explore a newly discovered CRISPR-associated signalling... -
Enzymes in a box: Engineering bacterial microcompartments for biotechnological applications
What if we could generate fuels directly just from Carbon dioxide and sunlight? In fact, the tiny green single celled microalgae are capable of doing... -
Enzymes in a box: Engineering bacterial microcompartments for biotechnological applications
The focus of this project is on metabolic engineering of microbes for the production of ester compounds that can be used as biofuels or... -
CRISPR-Enhanced: Towards better genome editing nucleases by directed evolution
Guided nucleases have revolutionized the field for genetic engineering. Through directed evolution, we aim to improve modern genome engineering... -
Chromosome segregation in Pyrococcus furiosus
Very little is known about chromosome segregation in Archaea. The aim of this research is to study chromosome segregation in the extremely... -
Seizing cell cycle of a synthetic cell
The perspective of a synthetic cell makes it possible to rewrite the rules governing life. This project focuses on the cell cycle, aiming at designing...