Biochemistry

Biochemistry is the study of the chemistry of life processes. Our research focuses on how biomolecules form, function and degrade inside cells. In short: "Cellular Biochemistry".

Our research

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Our Education

The Laboratory of Biochemistry provides a number of lecture series and practical courses for students.

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Selected publications

Plant embryogenesis. de Vries SC, Weijers D, Current Biology, 27, Issue 17, 2017, R870-R873. doi: dx.doi.org/10.1016/j.cub.2017.05.026

Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Boer, D.R.*, Freire-Rios, A.*, van den Berg, W.A.*, Saaki, T., Manfield, I.W., Kepinski, S., López-Vidrieo, I., Franco-Zorrilla, J.M., de Vries, S.C., Solano, R., Weijers, D.*, Coll, M.* Cell. 2014 Jan 30;156(3):577-89. doi: 10.1016/j.cell.2013.12.027

Transcriptome dynamics revealed by a gene expression atlas of the early Arabidopsis embryo. Palovaara J, Saiga S, Wendrich JR, van 't Wout Hofland N, van Schayck JP, Hater F, Mutte S, Sjollema J, Boekschoten M, Hooiveld GJ, Weijers D. Nat Plants. 2017 Nov;3(11):894-904. doi:10.1038/s41477-017-0035-3

The VAO/PCMH flavoprotein family. Ewing TA, Fraaije MW, Mattevi A, van Berkel WJH. Arch Biochem Biophys, 2017, 632:104-117. doi: 10.1016/j.abb.2017.06.022.

MetIDB: a publicly accessible database of predicted and experimental 1H NMR spectra of flavonoids. Mihaleva VV, te Beek TA, van Zimmeren F, Moco S, Laatikainen R, Niemitz M, Korhonen SP, van Driel MA, Vervoort J. Anal Chem. 2013 Sep 17;85(18):8700-7. doi: 10.1021/ac4016837. Epub 2013 Aug 26.

The ribosome restrains molten globule formation in stalled nascent flavodoxin. Houwman, J.A., André, E., Westphal, A.H., van Berkel, W.J.H. & van Mierlo, C.P.M. J. Biol. Chem. 291(50), 25911–25920. doi: 10.1074/jbc.M116.756205.

Colorful Packages: Encapsulation of Fluorescent Proteins in Complex Coacervate Core Micelles. Nolles A, Westphal AH, Kleijn JM, van Berkel WJH, Borst JW. Int J Mol Sci. 2017. doi:10.3390/ijms18071557.