Enzymes@Work - Research

Recent research highlights

Nature publication

Mical links semaphorins to F-actin disassembly.

R.J. Hung, U. Yazdani, J. Yoon, H. Wu, T. Yang, N. Gupta, Z. Huang, W.J.H. van Berkel & J.R. Terman Nature (2010) 463:823-827

JBC Paper of the Week

Identification of a gatekeeper residue that prevents dehydrogenases from acting as oxidases.

N.G. Leferink, M.W. Fraaije, H.J. Joosten, P.J. Schaap, A. Mattevi & W.J.H. van Berkel J Biol Chem (2009) 284:4392-4397 

PNAS paper

Multiple pathways guide oxygen diffussion into flavoenzyme active sites.

R. Baron, C. Riley, P. Chenprakhon, K. Thotsaporn, R.T. Winter, A. Alfieri, F. Forneris, W.J.H. van Berkel, P. Chaiyen, M.W. Fraaije, A. Mattevi & J.A. McCammon Proc Natl Acad Sci USA (2009) 106:10603 -10608 

Accelerated publication

Picosecond fluorescence relaxation spectroscopy of the calcium-discharged photoproteins aequorin and obelin.

B. van Oort, E.V. Eremeeva, R.B.M. Koehorst, S.P. Laptenok, H. van Amerongen, W.J.H. van Berkel, N.P. Malikova, S.V. Markova, E.S. Vysotski, A.J.W.G. Visser & J. Lee. Biochemistry (2009) 48:10486-10491

Current PhD research subjects

Enzymes@Work - Other Research projects