MSc Thesis Topic: Innate immunity to parasites in animals and plants

An increasing number of people in the world suffer from hyperimmune diseases (e.g. allergy, diabetes, multiple sclerosis).

The most widely used therapies are currently based on treatment with drugs known for their extraordinary side-effects. Our lab at the moment is looking into the possible treatment of these hyperimmune diseases with parasitic worms.

Parasitic worms./Picture: Geert Smant
Parasitic worms./Picture: Geert Smant

This program is inspired by the observations of worm capble of suppressing hyperimmune activities. People carrying worms infections are at a significantly lower risk of developing a hyperimmune condition. We want to understand the mechanism behind this immunomodulation of a host by a worm.