Publications

Rothia nasimurium strain:PT-32 Genome sequencing and assembly

Gaiser, R.A.; Medema, M.H.; Kleerebezem, M.; Baarlen, P. van; Wells, J.M.

Summary

Streptococcus suis is an important porcine and zoonotic pathogen for which there is no effective cross-protective vaccine. S. suis is the cause of significant economic losses to the pig production industry worldwide, and there is a need for alternative strategies to prevent colonization and invasive disease, especially in young pigs. We have explored the microbiota of healthy piglets with the aim to find commensal bacteria that can specifically kill or inhibit the growth of S. suis. Here we describe the identification and characterization of a commensal Rothia nasimurium strain from the porcine palatine tonsil that effectively inhibits a wide range of S. suis strains in vitro.