This report presents the key highlights and contributions from the conference ‘Measuring what matters in a ‘post-truth’ society’. This conference was held on the 6th of April 2017 in Wageningen, the Netherlands. This conference was the 10th annual ‘M&E on the Cutting Edge’ conference. These events are organised by Wageningen University & Research, Wageningen Centre for Development Innovation (CDI) in collaboration with partners, in this case Oxfam GB. The conference focused on understanding how we measure what matters, and use what matters, to change what should matter, in an era of post-truth, whilst aiming towards social inclusion and global development.