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Nature Nanotechnology cover: Nanopore trap for protein observations

Published on
November 16, 2021

The NEOtrap featured as Nature Nanotechnology cover article: Nanopore trap for protein observations.

An artistic depiction of the nanopore electro-osmotic trap (NEOtrap), formed by a DNA-origami sphere docked onto a solid-state nanopore. The leaky DNA origami plug stops protein flow through a nanopore and allows the hydrodynamic trapping and label-free observation of single proteins, enabling nucleotide-dependent protein conformation to be discriminated on the timescale of submilliseconds to hours.

Read our NEOtrap paper here: https://www.nature.com/articles/s41565-021-00958-5

and Nature Nanotech's News & Views by A. Aksimentiev: https://www.nature.com/articles/s41565-021-00968-3