In the coming years, we will be working to bring Organs-on-a-chip from lab to fab!
The chair group of Toxicology of Wageningen University is a partner in the 4.8 million euro TTW Perspective program 'SMART OoC', sponsored by NWO (Dutch Research Council). In this large programme we aim to bring organ on chips on a next level Currently, large-scale use by the pharma is not yet on the agenda due to the lack of a universal standard. There are many kinds of chips, each with its own design, dimensions and material. Moreover, the chips are difficult to fit into the workflow of the pharmaceutical industry and scaling up to larger numbers is very difficult. In short, they are designed for research, not for industry. This is what a consortium led by Jaap den Toonder (TU Eindhoven) is composed of 10 research groups of 8 universities, united in the Dutch 'organ-on-chip' consortium hDMT, want to change, together with 21 companies, 3 knowledge institutions and 2 foundations.
In the program, the Chair group of Toxicology we implement gut-on-chip systems for studies in collaboration with the consortium partners. Check this: https://www.youtube.com/watch?v=WdsMJkzCjeY.
The Dutch organ-on-chip consortium hDMT brought the following partners together for this NWO Perspective program: Amsterdam UMC/VUmc, Delft University of Technology, Eindhoven University of Technology, UMC Utrecht, Leiden University, Maastricht University, Twente University, Wageningen University & Research, 300MICRONS, Applikon, BioLamina, Convergence, Demcon, dsRAT Stichting Proefdiervrij, Galapagos, Genmab, Hy2Care, IBA Lifesciences, ibidi, Life Science Methods, LipoCoat, Micronit Microtechnologies, OnePlanet Research Center/imec, Poietis, PolyVation, provio, Qurin Diagnostics, ReumaNederland, RIVM, Spektrax, TissUse, TNO, Unilever Safety & Environmental Assurance Centre, Ushio INC.