We perform integrated assessments of water systems, in which we integrate knowledge on water systems and global change. To this end, we use a variety of models and observations. We combine modeling analyses with participatory approaches. Our water assessments focus on (1) the effect of changing global drivers on water systems, (2) adaptation and (3) mitigation strategies, comprising of novel approaches such as adaptive water management and ecosystem-based adaptation and (4) climate-water services. We thus take an integrated approach across the water, food and energy systems, at multiple spatial and temporal scales.