Laboratory of Cell Biology

The laboratory of Cell Biology studies the dynamics of cellular organization in relation to cell growth, cell division and the organization of cell walls. Welcome to our site.

Our research

We investigate how cells attain a well-ordered architecture. Special attention is given to the role of forces and physical principles that determine the dynamics of cellular life. We focus on the interactions that cytoskeletal filaments, microtubules and actin, have with each other and from there aim to understand the organization and functioning of large-scale cytoskeletal networks that have essential roles in shaping cells.

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Light Microscopy Centre

Get free access to up-to-date imaging facilities and make use of the DTL Technology Hotels.
The WLMC is part of the WISH and welcomes you to explore its imaging options available at Wageningen University & Research (Radix)
Last year almost 50% of the grant applications were rewarded!
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Our laboratory houses the Wageningen Light Microscopy Centre that welcomes researchers from inside and outside our university. The center provides advanced instrumentation and expertise for live cell imaging, food sciences and materials research.

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Plant Cytokinesis

New paper on plant Cytokinesis by de Keijzer et al. in current biology (January 2017)

Plants and animals synthesize and move large amounts of membranous material to construct a division plane for cell division. We now define short stretches of antiparallel microtubule overlap as membrane accumulation sites in moss plants. Dimensions of the dividing cell plate are set by kinesin-4 mediated shortening of these overlaps.

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Kastanjebloedingsziekte wordt veroorzaakt door een bacterie. Volgens de onderzoekers kan de bacterie niet tegen warmte. Er worden nu proeven gedaan door bomen "in te pakken" en te verwarmen met water. Zo hopen zij de bomen te genezen.

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A microscopic gas spring generates force inside cells

Researchers from the laboratory of Cell Biology publish in Cell in collaboration with groups in Dresden en Amsterdam. The work shows that microtubule crosslinkers of the Map65/Ase1/PRC1 family, conserved amongst plants and animals, generate directed forces during cell division.