Projects
-
Process development of recombinant AAV manufacturing using the Baculovirus Expression System
- Scalability is one of the main obstacles for the transfection-based manufacturing of pharmaceutical AAV vectors in mammalian cell lines. The usage of... -
A baculovirus expression system free of contaminating baculovirus particles (BACFREE)
- The BACFREE project aims to develop a baculovirus expression system that allows the production of pharmaceuticals free of contaminating baculovirus... -
Blood-feeding midges as models for the role of microbiomes in the transmission of diseases: a Global One Health approach
- The introduction of unknown pathogenic viruses can pose a major threat to livestock and human health. Recently, the Netherlands faced such a challenge... -
Towards broad, stable and durable resistance against Tomato spotted wilt virus (tospovirus).
- Breeding of resistance against TSWV sofar is limited to the availability of only two single dominant resistance (R) genes, namely Sw5 and Tsw.