AF16012 Nutrition to improve quality of life of IBS patients

Project

Food that contributes to a better quality of life for people with an irritable bowel

​Food that contributes to a better quality of life for people with an irritable bowel (IBS). That is the focus of this research project by Wageningen Food & Biobased Research.

Irritable Bowel Syndrome (IBS) is an illness that affects a large group of people. It is estimated that 10%-20% of the world's population suffers from some form of IBS, which decreases quality of life.

No adequate treatment

No adequate treatment is available at the moment. This is partly because of the heterogenous patient population and the complicated pathology, of which not all mechanisms are fully understood. IBS is a multi-factor illness in which the intestinal wall, the immune system, enteroendocrine cells, and the microbiota play an important role.

Changes in diet

Gastroenterologists often hear from patients that changes to their diet have the most impact on reducing the symptoms of IBS. However, it is unclear whether this is the same for every subgroup of patients, what mechanism causes this, and what food has the most significant positive impact.

The three most important objectives of this research project are:

The research is divided into three work packages:

    Publicaties