Analytical laboratories that perform chemical analysis on veterinary drugs, mycotoxins and pesticides need to demonstrate that their methods are fit for purpose. In this online course you will learn step by step to draft a validation plan for your own validation case. This includes the construction of a validation plan, the design of experiments, the assessment of analytical data and the preparation of a validation report.
Why attend this course?
Multiple validation approaches exist (Commission Implementing Regulation EU 2021/808, SANTE/12682/2019, CODEX CAC/GL 71-2009) and it is often unclear how to implement these and how to come to a practical set-up of experiments. In this course, you will learn the theoretical background on the validation of quantitative confirmatory methods and how to select and execute a cost-effective validation approach based on a practical validation plan. The training will briefly discuss all three approaches and then zoom in on CD 2002/657/EC, including this regulation's revision.
All participants in this course are invited to bring their own validation case study to apply all newly gained knowledge to their own laboratory practice. Preconstructed case studies are available in case you can’t bring your own. After successfully attending the online course, you will:
- Understand the phases to go through for a fit for purpose validation
- Be able to determine the relevant validation parameters
- Have a good understanding of the meaning of trueness, precision, CCα and CCß
- Be able to determine measurement uncertainty
- Be able to construct and execute a validation plan
- Have hands-on experience with the evaluation of the analytical data
- Be able to prepare a validation report
- Have applied all this knowledge in your own validation plan
Who is this course for?
Professionals with a technical background in industry, in governmental, commercial or academic laboratories in the area of food and feed safety residue analysis. At least a BSc or comparable is required in a relevant field. In addition work experience of at least 2 years is required in the field of chemical analysis of residues.
Programme and topics
This course offers you an attractive mix of live online sessions and self-study. The live online sessions are with experts and other students. The self-study is build up with pre-recorded presentations, readings, quizzes and assignments. Throughout the course you can interact on the learning platform directly with other students and experts via a discussion forum.
Structured in 7 modules, the following topics will be discussed:
- Introduction to the course
- Fundamentals - qualitative versus quantitative methods, performance characteristics and measurement uncertainty
- Design - selecting performance characteristics, minimum requirements, design of experiments
- Data evaluation – calculations and application
- Reporting – outcome assessment, validation report
- Other validation procedures – ongoing method validation, screening method, verification and extension
- Closure of the course
During the course 5 live sessions are scheduled:
- General live kick-off with course leaders on Tuesday 8 March 2022 at 9.00 am (GMT).
- Live Q&A sessions with experts on 17 and 22 March at 9.00 am (GMT) and on 30 March and 13 April 2022 at 8.00 am (GMT).
The sessions are recorded and can be watched later. But we highly recommend you to follow the general class outline and attend all live sessions to get the most out of your learning experience.
For a full overview of the schedule, topics and speakers download the flyer.
The courseleader is Dr. ing. B. J. A. (Bjorn) Berendsen, Wageningen Food Safety Research. Other experts involved are Marco Blokland MSc and Carmen Bot MSc, all Wageningen Food Safety Research.