This group focuses on investigating and exploiting genetic variation and biodiversity. It develops and employs various genetic and genomic technologies (including motif directed profiling) to assess biodiversity between and within species, focusing on genetic variation at the allelic level.
Developing technologies for high throughput analysis is another point of attention. Structure and inheritance of the genetic variation is studied using genetic marker maps and through haplotype reconstruction. The study of neutral genetic variation is used in phylogenetic studies and for quantification of dispersal and gene flow.
Key focus area's
The study of functional diversity includes allelic variation for various quality and resistance traits and for the occurrence of allergens (PR10 proteins in apple and birch, gluten protein families in wheat).
Breeding for varieties with reduced allergenicity
In the Western society, prevalence and severity of allergies are rapidly increasing. Our research focus is on solutions for allergy-related matters in the pre-medical stage. We study the diversity of allergens in germplasm, and develop strategies to lower the amount of allergens by breeding. In this way we aim to prevent rather than cure.
How to Assure That Farmers Apply New Technology According to Good Agricultural Practice: Lessons From Dutch Initiatives
Frontiers in Environmental Science 6 (2018). - ISSN 2296-665X - 5 p.
Ontrafeling rozengenen nuttig voor veredeling op kwaliteit en resistentie : Roos en aardbei genetisch bijna hetzelfde : plantkunde : achtergrond
Onder Glas 15 (2018)9. - p. 10 - 11.
Correction to : New traits in crops produced by genome editing techniques based on deletions (Plant Biotechnology Reports, (2017), 11, 1, (1-8), 10.1007/s11816-017-0425-z)
Plant Biotechnology Reports 12 (2018)5. - ISSN 1863-5466 - p. 375 - 375.
Tracking disease resistance deployment in potato breeding by enrichment sequencing
Plant Biotechnology Journal (2018). - ISSN 1467-7644
Omics analyses of potato plant materials using an improved one-class classification tool to identify aberrant compositional profiles in risk assessment procedures
Food Chemistry (2018). - ISSN 0308-8146
Balans van de Leefomgeving 2018 : Nederland duurzaam vernieuwen
Den Haag : Planbureau voor de Leefomgeving - p.
Gene editing using CRISPR/Cas9 to modify or remove gliadins from wheat and produce coeliac disease epitope-free wheat
In: Proceedings of the 31st Meeting of the Working Group on Prolamin Analysis and Toxicity / , Koehler, Peter. - Minden, Germany - ISBN 9783000588020 - p. 63 - 68.
QTL mapping in diploid potato by using selfed progenies of the cross S. tuberosum × S. chacoense
Euphytica 214 (2018)7. - ISSN 0014-2336
A high-quality genome sequence of Rosa chinensis to elucidate ornamental traits
Nature Plants 4 (2018). - ISSN 2055-026X - p. 473 - 484.
BIOFOS: A micro-ring resonator-based biophotonic system for food analysis - Application to olive oil contaminants
In: Proceedings of the 8th International Olive Symposium. - : International Society for Horticultural Science (Acta Horticulturae ) - ISBN 9789462611955 - p. 505 - 509.
- Jaap Wolters
- Gerard Bijsterbosch
- Christel Engelen
- Johan Willemsen
- Jeroen Berg
- Peter Vos
- Izan Shairul Binti Ramiee
- Madhuri Madduri
- Stefano Pessina
- Dennis Meijer
- Manos Domazakis
- Mario di Guardo
- Nur Fatihah Bint Hasan Nudin