This group focuses on investigating and exploiting genetic variation and biodiversity. It develops and employs various genetic and genomic technologies (including motif directed profiling) to assess biodiversity between and within species, focusing on genetic variation at the allelic level.
Developing technologies for high throughput analysis is another point of attention. Structure and inheritance of the genetic variation is studied using genetic marker maps and through haplotype reconstruction. The study of neutral genetic variation is used in phylogenetic studies and for quantification of dispersal and gene flow.
Key focus area's
The study of functional diversity includes allelic variation for various quality and resistance traits and for the occurrence of allergens (PR10 proteins in apple and birch, gluten protein families in wheat).
Breeding for varieties with reduced allergenicity
In the Western society, prevalence and severity of allergies are rapidly increasing. Our research focus is on solutions for allergy-related matters in the pre-medical stage. We study the diversity of allergens in germplasm, and develop strategies to lower the amount of allergens by breeding. In this way we aim to prevent rather than cure.
Some thoughts on how to use markers in tetraploid rose breeding
Acta Horticulturae 1232 (2019). - ISSN 0567-7572 - p. 1 - 6.
Tracking disease resistance deployment in potato breeding by enrichment sequencing
Plant Biotechnology Journal 17 (2019)2. - ISSN 1467-7644 - p. 540 - 549.
Bioimpuls, biologische aardappelveredeling
BIOFOS: micro-ring resonator-based biophotonic system for food analysis. Nut mycotoxin detection
In: Proceedings of the 7th International Symposium on Almonds and Pistachios. - : International Society for Horticultural Science (Acta Horticulturae ) - ISBN 9789462612167 - p. 339 - 343.
How to Assure That Farmers Apply New Technology According to Good Agricultural Practice: Lessons From Dutch Initiatives
Frontiers in Environmental Science 6 (2018). - ISSN 2296-665X - 5 p.
Ontrafeling rozengenen nuttig voor veredeling op kwaliteit en resistentie : Roos en aardbei genetisch bijna hetzelfde : plantkunde : achtergrond
Onder Glas 15 (2018)9. - p. 10 - 11.
Correction to: New traits in crops produced by genome editing techniques based on deletions
Plant Biotechnology Reports 12 (2018)5. - ISSN 1863-5466 - p. 375 - 375.
Omics analyses of potato plant materials using an improved one-class classification tool to identify aberrant compositional profiles in risk assessment procedures
Food Chemistry (2018). - ISSN 0308-8146
Balans van de Leefomgeving 2018 : Nederland duurzaam vernieuwen
Den Haag : Planbureau voor de Leefomgeving - p.
Gene editing using CRISPR/Cas9 to modify or remove gliadins from wheat and produce coeliac disease epitope-free wheat
In: Proceedings of the 31st Meeting of the Working Group on Prolamin Analysis and Toxicity / , Koehler, Peter. - Minden, Germany - ISBN 9783000588020 - p. 63 - 68.
- Jaap Wolters
- Gerard Bijsterbosch
- Christel Engelen
- Johan Willemsen
- Jeroen Berg
- Peter Vos
- Izan Shairul Binti Ramiee
- Madhuri Madduri
- Stefano Pessina
- Dennis Meijer
- Manos Domazakis
- Mario di Guardo
- Nur Fatihah Bint Hasan Nudin