This group focuses on investigating and exploiting genetic variation and biodiversity. It develops and employs various genetic and genomic technologies (including motif directed profiling) to assess biodiversity between and within species, focusing on genetic variation at the allelic level.
Developing technologies for high throughput analysis is another point of attention. Structure and inheritance of the genetic variation is studied using genetic marker maps and through haplotype reconstruction. The study of neutral genetic variation is used in phylogenetic studies and for quantification of dispersal and gene flow.
Key focus area's
The study of functional diversity includes allelic variation for various quality and resistance traits and for the occurrence of allergens (PR10 proteins in apple and birch, gluten protein families in wheat).
Breeding for varieties with reduced allergenicity
In the Western society, prevalence and severity of allergies are rapidly increasing. Our research focus is on solutions for allergy-related matters in the pre-medical stage. We study the diversity of allergens in germplasm, and develop strategies to lower the amount of allergens by breeding. In this way we aim to prevent rather than cure.
Polynucleotide constructs and methods of gene editing using CPF1Octrooinummer: WO2019238772, gepubliceerd: 2019-12-19.
Green Plant Biotechnology at workWageningen : Groen Kennisnet
Some thoughts on how to use markers in tetraploid rose breedingActa Horticulturae 1232 (2019). - ISSN 0567-7572 - p. 1 - 6.
Kan coeliakiepatiënt straks weer gewoon eten? Tarwe met veilige glutenKan coeliakiepatiënt straks weer gewoon eten? Tarwe met veilige gluten, Resource 13(2019)11 p. 10, 2019-01-21, Albert Sikkema, https://edepot.wur.nl/4698
Tracking disease resistance deployment in potato breeding by enrichment sequencingPlant Biotechnology Journal 17 (2019)2. - ISSN 1467-7644 - p. 540 - 549.
Omics analyses of potato plant materials using an improved one-class classification tool to identify aberrant compositional profiles in risk assessment proceduresFood Chemistry 292 (2019). - ISSN 0308-8146 - p. 350 - 358.
Bioimpuls, biologische aardappelveredeling
BIOFOS: micro-ring resonator-based biophotonic system for food analysis. Nut mycotoxin detectionIn: Proceedings of the 7th International Symposium on Almonds and Pistachios. - : International Society for Horticultural Science (Acta Horticulturae ) - ISBN 9789462612167 - p. 339 - 343.
Kennisdag Fruit 2018
How to Assure That Farmers Apply New Technology According to Good Agricultural Practice: Lessons From Dutch InitiativesFrontiers in Environmental Science 6 (2018). - ISSN 2296-665X - 5 p.
- Johan Willemsen
- Manos Domazakis
- Aurelie Jouanin
- Aviv Andriani
- Carolina Aguilera Galvez
- Xiao Lin
- Yerisf Torres Ascurra
- Xinfang Wang
- Thijs van Dijk
- Daniel Danial
- Angela Machacilla
- Bjarne Larsen
- Giorgio Tumino
- Reinhafd Simon