Presentation

Modeling regulation and kinetics of photosynthesis: big models and small data

Organised by Biometris
Date

Fri 20 March 2015 11:00 to 12:00

Venue Radix, gebouwnummer 107
Room M6

In the field of plant photosynthesis research, there is a large gap between knowledge at the molecular scale, generated "in the lab", and knowledge at the scale of whole organism obtained under "natural" dynamic conditions (field, greenhouse, etc). There is an increasing interest in bridging this gap and dynamic, mechanistic models represent a great tool for such purpose as they enable knowledge integration and predictive analysis of the dynamics of the system. However, whereas photosynthesis is among the best known pathways in plant metabolism, our ability to quantify accurately in vivo is limited, leading to the situation where one can build large models (based on expert knowledge) with very little data to test them. In this talk I will discuss about the challenges of modelling the kinetics and metabolic regulation of photosynthesis and the strategies that I am following to address them with special emphasis on the role of expert knowledge, the importance of considering in vivo kinetics and the need for complementary simple and complex models.In the field of plant photosynthesis research, there is a large gap between knowledge at the molecular scale, generated "in the lab", and knowledge at the scale of whole organism obtained under "natural" dynamic conditions (field, greenhouse, etc). There is an increasing interest in bridging this gap and dynamic, mechanistic models represent a great tool for such purpose as they enable knowledge integration and predictive analysis of the dynamics of the system. However, whereas photosynthesis is among the best known pathways in plant metabolism, our ability to quantify accurately in vivo is limited, leading to the situation where one can build large models (based on expert knowledge) with very little data to test them. In this talk I will discuss about the challenges of modelling the kinetics and metabolic regulation of photosynthesis and the strategies that I am following to address them with special emphasis on the role of expert knowledge, the importance of considering in vivo kinetics and the need for complementary simple and complex models.