New applications of the interaction between diols and boronic acids

PhD defence

New applications of the interaction between diols and boronic acids

PhD candidate FL (Florine) Duval
Promotor prof.dr. JT (Han) Zuilhof
Co-promotor dr. TA (Teris) van Beek
Organisation Wageningen University & Research, Laboratory for Organic Chemistry
Date

Fri 9 October 2015 16:00 to 17:30

Venue Aula, gebouwnummer 362
Generaal Foulkesweg 1
362
6703 BG Wageningen
0317-483592

Summary

Imagine a man and a woman who meet, hold both hands and form a dancing pair. In the chemistry world, a “diol” is like a microscopic man and a “boronic acid” is like a microscopic woman. When they hold both “hands”, they form a chemical dancing pair. Boronic acids are very useful in science and medicine, but first one needs to make them. And while making them, one needs to detect them. To detect boronic acids, we used alizarin, a very special diol: when alizarin forms a dancing pair with a boronic acid, “he” shines like a white shirt under nightclub black lights. Thus, “he” stands out from the crowd and you know where “miss” boronic acid was hiding. Very handy!