Thesis subject

Distribution and variation of downy mildew resistance genes in natural populations of wild lettuce

Lettuce downy mildew is one of the most serious diseases of lettuce (Lactuca sativa). It is caused by the oomycete Bremia lactucae, a pathogen notorious for its capability to rapidly overcome host resistance. As a result most lettuce cultivars lack nowadays adequate resistance to new Bremia races. Natural populations of related Lactuca species are regarded as important sources of novel genetic resistance.

Start date

01/12/2025

End date

3107/2026

This project aims to evaluated Bremia resistance in wild Lactuca populations from Central Asia, which are currently underrepresented in gene bank centres, by combining phenotypic and genotypic analyses.

You will:

  • analyse biogeographical distribution and population structures of wild lettuce species
  • explore natural variation in disease resistance with pathogen assays
  • determine frequency and genetic variation in resistance genes across wild lettuce populations
  • perform phylogenetic and population genetic studies