Thesis subject
What is the role of these Really Interesting New Genes in the resistance mechanism?
Evidence exists that RING finger motif proteins have a role in resistance.
The presence of a family of 4 members with a high homology to RMA1 (a RING finger motif protein) on the 187 kb sequence from SH that harbours the Gpa2/Rx1 locus could have a biological relevance for Rx1 mediated PVX resistance and Gpa2 mediated G. pallida resistance. We would like to answer this question through over expression and silencing in potato and tobacco.