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Projects - prof.dr. JM (Jerry) Wells
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Antibacterial (Nano)medicines Development
The growing problem of bacterial multi-drug resistance (MDR) requires the urgent development of novel antibacterials with different mechanisms of... -
yycF/G as a drug target in emerging zoonotic pathogen Streptococcus suis
Two-component systems (TCSs) are used by bacteria to efficiently adapt to environmental changes such as temperature, osmolarity, chemo-attractants and... -
Heat treated bacteria and immunity (Nestec II)
Modulation of the immune system is one of the most plausible mechanistic concepts of probiotic function. To understand the mechanisms involved, more... -
Bacteriocins from porcine microbiota to prevent Streptococcus suis carriage and infection
There is a growing interest in identifying commensal organisms that produce bacteriocins against veterinary pathogens as this approach could be an... -
The aryl hydrocarbon receptor (AhR)
Large numbers of intra-epithelial lymphocytes (IELs) intercalate between epithelial cells in the intestine and play a key role in resistance to... -
Role of mucus in intestinal immune barrier
The intestinal mucus layer has a critical role in human gut health and human health in general. -
Control of competence for DNA transformation in Streptococcus suis
Streptococcus suis (S. suis) is one of the major bacterial pathogens of pigs worldwide and is considered an important zoonotic pathogen due to the... -
Fibebiotics
As part of the European Commission’s Seventh Framework Program, a 4.5 years research program to study the effects of polysaccharides on immune... -
Food for the gatekeeper
The homeostasis of the small intestine and its mucosal immune system can be modulated by various food-products. In order to efficiently study, but...