Publications
Class 2 Type V CRISPR-Cas prime editing
De Vleesschauwer, David; Meulewaeter, Frank; Kuijpers, Anne-Marie; Staals, Raymond Hubert Josèphe; Van Der Oost, John; D'Halluin, Katelijn; Swartjes, Thomas; Verhagen, Han; Villegas Warren, Ricardo
Summary
The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a CRISPR-Cas class 2 type V prime editing system, including a prime editor, a prime editor complex, a prime editing guide RNA system as well as the means and methods for the modification of a nucleic acid sequence of interest with the prime editing system of the present invention.