Metabolomics as an emerging strategy for the investigation of yogurt components

Settachaimongkon, S.; Valenberg, H.J.F. van; Smid, E.J.


The advanced development in metabolomics allows discovery of a wide range of metabolites in complex biological systems including food matrices. This analytical approach provides opportunities to attain a global metabolite profile and discover potential biomarkers and various chemical contaminants that can be directly correlated with the quality, safety, and authenticity of the food product. This chapter provides information on the applications of metabolomics as an emerging strategy for the investigation of yogurt components. The fundamentals of metabolomics and statistical interpretation of data are described. The implementation of metabolomics as part of foodomics technologies is discussed. Some of the noteworthy studies and possibility for using an advanced high-throughput metabolomics platform in assessing and predicting the quality of yogurt are highlighted. Finally, the application of nuclear magnetic resonance-based and mass spectrometry-based technologies for determining a wide range of metabolites associated with the metabolism of starter cultures and probiotics during yogurt fermentation and storage are discussed.

Keywords: Chemometrics; Dairy; Fermented milk; Flavor; Lactic acid bacteria;
Metabolite profile; Metabolomics; Milk; Probiotics; Starter culture