Rolf Berge

Rolf Berge participates in the Mitofood project; a research community for nutritional optimization of mitochondrial function for health promotion and disease resistance.

Prof. dr. Rolf Berge

Institute of Medicine, Section of Medical Biochemistry
The Lipid Research Group, University of Bergen
Haukeland University Hospital
N-5021 Bergen
NORWAY
Tel +47 5597 3098
Fax +47 5597 3115

E-mail: rolf.berge@ikb.uib.no

Expertise

Influence of bioactive components (lipids, modified fatty acids and peptides) on PPAR-dependent and -independent pathways including mitochondrial function on metabolic syndrome and cell death

Relevant projects and functions

  • Partner in the EU-FP6 integrated project LIPGENE
  • Member of the ICBL Steering Committee
  • Founder of the biotechnological company Thia Medica

Group structure

1 Professor (M), 2 senior scientists (M), 2 post-docs (1 M, 1 F), 2 PhD students (F), 5 technicians (F)

Selected publications

  1. Grav HJ, Tronstad KJ, Gudbrandsen OA, Berge K, Fladmark KE, Martinsen TC, Waldum H, Wergedahl H, Berge RK. 2003. Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated receptor-alpha independent induction of UCP-2 expression. J Biol Chem 278: 30525-33
  2. Tronstad KJ, Gjertsen BT, Krakstad C, Berge K, Brustugun OT, Doskeland SO, Berge RK. 2003. Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells. Bhem Biol 10: 609-18.