Thesis subject
The role of mitochondrial dynamics in aging
To provide an overview of mitochondrial dynamics and how this may be disturbed in aging.
Background: Mitochondria play an important role in many physiological processes including oxidative phosphorylation, and are crucial for cellular function. Mitochondrial dynamics (i.e. mitochondrial fission and fusion and mitochondrial biogenesis and mitophagy) are crucial processes to maintain a healthy mitochondrial network. Nevertheless, it has been described that mitochondrial functioning declines with age.
Questions: What is the role of mitochondrial dynamics in the aging process? What processes of mitochondrial dynamics are affected by aging?
Aims: To provide an overview of mitochondrial dynamics and how this may be disturbed in aging.