Torsten Bohn

Dr. Torsten Bohn

Email: bohn@lippmann.lu

Expertise

• Investigation of polyphenols and cartotenoids and factors impacting their bioavailability in humans.
• The relation of phytochemicals such as polyphenols and carotenoids and their impact on chronic diseases, with a focus on biomarkers associated with the metabolic syndrome and obesity.
• The relation between antioxidative properties of polyphenols and carotenoids and biomarkers of inflammation, such as inflammation in the gut, and signalling cascades and intracellular mechnisms involved in inflammation.

Relevant projects and functions

• CARO: Determination of factors influencing carotenoid absorption, their precursors and degradation products, by Caco-2 cell bioaccessibility studies coupled to in-vitro digestion. Project leader.
• Neuroprot: Identification and characterization of polyphenol constituents in luxembourgish aplle and mirabelle cultivars, and cytoprotective effects studied by PC12 neuronal cell lines. Project leader.
• Protheart: Identification of new biomarkers of heart failure by proteomic analysis of plasma proteins. Co-PI.

Group structure

Within the Nutrition and Toxicology group there are 21 people, of which are 7 women. The research team is structured into 3 project leaders, 2 technicians, 3 PhD students, and researchers.

Selected publications

1. Bohn, T. (2008). Factors influencing the bioavailability of non-provitamin A carotenoids. (Review) Curr. Nutr. Food Sci, 4, 250-58.
2. Bohn, T, Tian, Q, Schwartz, SJ, Failla, ML (2007). Fat-free phytosterol products supplemented to test meals can reduce cholesterol micellarization and inhibit cholesterol accumulation by Caco-2 cells as determined enzymatically and by stable isotope techniques. J. Food Sci.Agric. 55, 267-72.