Publicaties/publications Mond-en-klauwzeer/Foot and mouth disease

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Elnekave, E., Dekker, A., Eble, P., van Hemert-Kluitenberg, F., Gelman, B., Storm, N., Klement, E. 2016. The long term effect of age and maternally derived antibodies against foot and mouth disease on the serological response following vaccination in young dairy calves. Vaccine 34: 4927-4934. WOT-01-003-011. Doi 10.1016/j.vaccine.2016.07.052

Elnekave, E., Dekker, A., Eble, P., van Hemert-Kluitenberg, F., Gelman, B., Storm, N., Klement, E. 2016. The serological response against foot and mouth disease virus elicited by repeated vaccination of dairy cattle. Vaccine 34: 4920-4926. WOT-01-003-011. Doi 10.1016/j.vaccine.2016.08.054

Aldo Dekker, Gilles Chénard, Norbert Stockhofe, Phaedra Eblé. 2016. Proper timing of foot-and-mouth disease vaccination of piglets with maternally derived antibodies will maximise expected protection levels. Front. Vet. Sci. 3: 52. doi: 10.3389/fvets.2016.00052. WOT-01-003-011.

Colenutt, C, Gonzales, JL, Paton, DJ, Gloster, J, Nelson, N & Sanders, C. 2016, 'Aerosol transmission of foot-and-mouth disease virus Asia-1 under experimental conditions' Veterinary Microbiology, vol 189, pp. 39-45., 10.1016/j.vetmic.2016.04.024

Blanco, E., Guerra, B., de la Torre, B. G., Defaus, S., Dekker, A., Andreu, D., Sobrino, F. 2016. Full protection of swine against foot-and-mouth disease by a bivalent B-cell epitope dendrimer peptide. Antiviral Res. 129: 74-80. Doi 10.1016/ j.antiviral.2016.03.005. WOT-01-003-011

Tekleghiorghis, T., Moormann, R. J., Weerdmeester, K., Dekker, A. 2016. Foot-and-mouth disease transmission in Africa: implications for control, a review. Transbound. Emerg. Dis. 63: 136-151. WOT-01-003-011. DOI: 10.1111/tbed.12248.

C. Bravo de Rueda, A. Dekker, P. L. Eblé, M.C.M. de Jong. 2015. Vaccination of cattle only is sufficient to stop FMDV transmission in mixed populations of sheep and cattle. Epidemiol. Infect. 143: 2279-2286. WOT-01-003-011

Harmsen, M. M., Fijten, H. P., Westra, D. F., Dekker, A. 2015. Stabilizing effects of excipients on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles during storage as oil-emulsion vaccine. Vaccine 33: 2477-2484. WOT-01-003-011

C. Bravo de Rueda, M.C.M. de Jong, P. L. Eblé, A. Dekker. 2015. Quantification of transmission of foot-and-mouth disease virus caused by an environment contaminated with secretions and excretions from infected calves. Vet. Res. 46: 43. WOT-01-003-011.

P.L. Eblé, K. Orsel, F. van Hemert-Kluitenberg, A. Dekker. 2015. Transmission characteristics and optimal diagnostic samples to detect an FMDV infection in vaccinated and non-vaccinated sheep. Vet. Microbiol. 177: 69-77. WOT-01-003-011

Roche, S. E., Garner, M. G., Sanson, R. L., Cook, C., Birch, C., Backer, J. A., Dube, C., Patyk, K. A., Stevenson, M. A., Yu, Z. D., Rawdon, T. G., Gauntlett, F. 2015. Evaluating vaccination strategies to control foot-and-mouth disease: a model comparison study. Epidemiol. Infect. 143: 1256-1275.

Paton, D.J., Füssel, A-E., Vosloo, W., Dekker, A., de Clerq, K. 2014. The use of serosurveys following emergency vaccination, to recover the status of “foot-and-mouth disease free where vaccination is not practised”. Vaccine 32: 7050-7056.

Tekleghiorghis, T., Moormann, R. J., Weerdmeester, K., Dekker, A. 2014. Serological Evidence Indicates that Foot-and-Mouth Disease Virus Serotype O, C and SAT1 are most Dominant in Eritrea. Transbound. Emerg. Dis. 61: e83-e88. WOT-01-003-011

Jamal, S. M., Shah, S. I., Ali, Q., Mehmood, A., Afzal, M., Afzal, M., Dekker, A. 2014. Proper Quality Control of Formulated Foot-and-Mouth Disease Vaccines in Countries with Prophylactic Vaccination is Necessary. Transbound. Emerg. Dis. 61: 483-489. doi: 10.1111/tbed.12051 WOT-01-003-011

Bari, F. D., Parida, S., Tekleghiorghis, T., Dekker, A., Sangula, A., Reeve, R., Haydon, D. T., Paton, D. J., Mahapatra, M. 2014. Genetic and antigenic characterisation of serotype A FMD viruses from East Africa to select new vaccine strains. Vaccine 32: 5794-5800.

Tekleghiorghis, T., Weerdmeester, K., van Hemert-Kluitenberg, F., Moormann, R. J., Dekker, A. 2014. No significant differences in the breadth of the foot-and-mouth disease serotype A vaccine. induced antibody responses in cattle, using different adjuvants, mixed antigens and different routes of administration. Vaccine 32: 5330-5336.

Dekker, A., Eblé, P, Stockhofe, N., Chénard, G. 2014. Intratypic heterologous vaccination of calves can induce an antibody response in presence of maternal antibodies against foot-and-mouth disease virus. BMC Vet. Res. 10: 127.

Carla Bravo de Rueda, Mart C. M. de Jong, Phaedra L. Eblé, Aldo Dekker. 2014. Estimation of the transmission of foot-and-mouth disease virus from infected sheep to cattle. Vet. Res. 45: 58.

Tekleghiorghis, T., Weerdmeester, K., van Hemert-Kluitenberg, F., Moormann, R. J., Dekker, A. 2014. Comparison of test methodologies for foot-and-mouth disease virus serotype A vaccine matching. Clin. Vaccine Immunol. 21: 674-683.

Jamal, S. M., Shah, S. I., Ali, Q., Mehmood, A., Afzal, M., Afzal, M., Dekker, A. 2014. Proper Quality Control of Formulated Foot-and-Mouth Disease Vaccines in Countries with Prophylactic Vaccination is Necessary. Transboundary and Emerging Diseases. doi: 10.1111/tbed.12051 WOT-01-003-011

Carla Bravo de Rueda, Aldo Dekker, Phaedra L. Eblé, MartC. M. de Jong. 2014. Identification of factorsassociated with increased excretion of Foot-and-Mouth Disease Virus. Prev. Vet.Med. Vol 113, Issue 1, January 14.WOT-01-003-011

Rincon, V.; Rodriguez-Huete, A.; Lopez-Arguello, S.; Ibarra-Molero, B.; Sanchez-Ruiz, J.M.; Harmsen, M.M.; Mateu, M.G., 2014, Identification of the structural basis of thermal lability of a virus provides a rationale for improved vaccines. Structure 22, 1560-1570.

Backer, J.A., Hagenaars, T.J., Nodelijk, G.  and Van Roermund, H.J.W. 2012. Vaccination against foot-and-mouthdisease I: Epidemiological consequences, Prev. Vet. Med. 107: 27-40,doi:10.1016/ j.prevetmed.2012.05.012

Backer, J.A., Engel, B., Dekker, A.  and Van Roermund, H.J.W. 2012. Vaccination against foot-and-mouthdisease II: Regaining FMD-free status. Prev. Vet. Med. Prev. 107: 41-50,doi:10.1016/ j.prevetmed.2012.05.013

Harmsen M.M., Fijten H.P., Westra D.F., Coco-Martin J.M. 2011. Effect of thiomersal on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles as assessed by novel ELISAs specific for either 146S or 12S particles. Vaccine 29, 2682-2690.

Harmsen, M.M., Jansen, J., Westra, D.F., Coco-Martin, J.M., Characterization of foot-and-mouth disease virus antigen by surface-enhanced laser desorption ionization-time of flight-mass spectrometry in aqueous and oil-emulsion formulations. Vaccine 2010; 28: 3362-3370. doi:10.1016/j.vaccine.2010.02.084

Orsel, K., Bouma, A., Dekker, A., Stegeman, J.A., Jong, M.C.M. de 2009. Foot and mouth disease virus transmission during the incubation period of the disease in piglets, lambs, calves, and dairy cows. Preventive Veterinary Medicine 88; 158–163

Eblé, P.L., Weerdmeester, K., van Hemert-Kluitenberg, F., Dekker, A. 2009 Intradermal vaccination of pigs against FMD with 1/10 dose results in comparable vaccine efficacy as intramuscular vaccination with a full dose. Vaccine 27; 1272–1278

Harmsen, M.M., Fijten, H.P.D., Engel, B., Dekker, A., Eble, P.L., 2009, Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs. Vaccine 27, 1904-1911.       

Goris, N.E., Eble, P.L., de Jong, M.C.M., De Clercq, K., 2009, Quantification of Foot-and-mouth Disease Virus Transmission Rates Using Published Data. Altex alternativen zu tierexperimenten 26, 52-54.

de Vos C.J., Nielen M., Lopez E., Elbers A.R., Dekker A. 2009. Probability of Exporting Infected Carcasses from Vaccinated Pigs Following a Foot-and-Mouth Disease Epidemic. Risk Anal. Available on line.

Harmsen, M.M., van Solt, C.B., Fijten, H.P. 2009. Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by N-glycosylation. Appl. Microbiol. Biotechnol. In press

Orsel, K., Dekker, A., Stegeman, J.A., de Jong, M.C.M., Bouma, A. 2009. Different infection parameters between dairy cows and calves after an infection with foot-and-mouth disease virus. Vet. J. In press

Harmsen MM, Fijten HP, Dekker A, Eblé PL. Passive immunization of pigs with bispecific llama single-domain antibody fragments against foot-and-mouth disease and porcine immunoglobulin. Vet Microbiol. 2008 Nov 25;132(1-2):56-64. Epub 2008 Apr 30

Piek, C.J., Junius, G., Dekker, A., Schrauwen, A., Slappendel, R.J., E. Teske. 2008. Idiopathic immune- mediated haemolytic anaemia: treatment outcome and prognostic factors in 149 dogs. Journal of veterinary internal medicine 22: 366-373

Eblé, P.L., de Koeijer, A.A., de Jong, M.C.M., Engel, B., Dekker, A. 2008. A meta-analysis quantifying transmission parameters of FMDV strain O Taiwan among non-vaccinated and vaccinated pigs. Preventive Veterinary Medicine 83(1): 98–106

Chénard, G., Selman, P., Dekker. A. Cedivac-FMD can be used according to a marker vaccine principle. Vet. Microbiol. 2008; 128: 65-71

Tenzin, Dekker, A., Vernooij, J.C.M., Bouma, A. Stegeman, J.A. 2008. Rate of Foot-and-mouth Disease Virus Transmission by Carriers Quantified from Experimental Data. Risk Analysis 28 (2); 303-309

Dekker, A., Samin, D.J., Greiner, M., Bergmann, I.E., Paton, D., Grazioli, S., de Clercq, K., Brocchi, E. 2008. Use of continuous results to compare ELISAs for the detection of antibodies to non-structural proteins of foot-and-mouth disease virus. Vaccine 26; 2723 – 2732

Orsel, K., Roest, H.I.J., Elzinga - Bril, E.M., van Hemert-Kluitenberg, F., Dekker, A. 2008. Detection of foot-and-mouth disease virus in infected pigs by RT-PCR four weeks after challenge. Veterinary Record 162(23); 753 - 754

Engel, B., Buist, W., Orsel, K., Dekker, A., de Clercq, K., Grazioli, S., van Roermund, H. 2008. A Bayesian evaluation of six diagnostic tests for foot-and-mouth disease for vaccinated and non-vaccinated cattle. Preventive veterinary medicine 86; 124–138

Jamal, S.M., Bouma, A., van den Broek, J., Stegeman, J.A., Chénard, G. Dekker, A. 2008. Foot-and-mouth disease vaccine potency testing: the influence of serotype, type of adjuvant, valency, fractionation method, and virus culture on the dose-response curve in cattle. Vaccine 26; 6317–6321

Eblé, P.L., Bouma, A., Weerdmeester, K., Stegeman, J.A., Dekker, A. 2007. Serological and mucosal immune responses after vaccination and infection with FMDV in pigs. Vaccine 25 (6): 1043-1054

Orsel, K., de Jong, M.C.M., Bouma, A., Stegeman, J.A., Dekker, A. 2007. The effect of vaccination on foot and mouth disease virus transmission among dairy cows. Vaccine 25 (2): 327-335

Harmsen, M.M., van Solt, C.B., Fijten, H.P.D., van Keulen, L., Rosalia, R.A., Weerdmeester, K., Cornelissen, A.H.M., De Bruin, M.G.M., Eblé, P.L., Dekker, A. 2007. Passive immunization of guinea-pigs with llama single-domain antibody fragments against foot-and-mouth disease. Veterinary Microbiology 120 (3-4): 193-206

Orsel, K., Dekker, A., Bouma, A., Stegeman, J.A., de Jong, M.C.M. 2007. Quantification of foot and mouth disease virus excretion and transmission within groups of lambs with and without vaccination.Vaccine 25(14): 2673-2679.

Orsel, K., de Jong, M.C., Bouma, A., Stegeman, J.A., Dekker, A. 2007.Foot and mouth disease virus transmission among vaccinated pigs after exposure to virus shedding pigs. Vaccine 25(34): 6381-6391.

Dekker, A., Dercksen, D., Snoep, J., Wuijckhuise, L. van. 2007. Mond-en-klauwzeer en bluetongue: verschillen en overeenkomsten. Tijdschrift voor diergeneeskunde 132(18): 695 - 701

Eblé, P.L., de Bruin, M.G.M., Bouma, A., van Hemert-Kluitenberg, F., Dekker, A. 2006. Comparison of immune responses after intra-typic heterologous and homologous vaccination against foot-and-mouth disease virus infection in pigs. Vaccine 24 (9): 1274-1281

Eblé, P.L., de Koeijer, A.A., Bouma, A., Stegeman, A., Dekker, A. 2006. Quantification of within- and between-pen transmission of Foot-and-Mouth disease virus in pigs. Veterinary Research 37 (5): 647-654

Brocchi, E., Bergmann, I.E., Dekker, A. Paton, D.J., Sammin, D.J., Greiner, M., Graziolia, S.,De Simone, F., Yadin, H., Haas, B., Bulut, N., Malirat, V., Neitzert, E., Goris, N., Parida, S., Sørensen, K., De Clercq, K. 2006. Comparative evaluation of six ELISAs for the detection of antibodies to the non-structural proteins of foot-and-mouth disease virus. Vaccine 24 (47-48): 6966-6979

Paton, D.J., De Clercq, K., Greiner, M., Dekker, A., Brocchi, E., Bergmann, I., Sammin, D.J., Gubbins, S., Parida, S. 2006. Application of non-structural protein antibody tests in substantiating freedom from foot-and-mouth disease virus infection after emergency vaccination of cattle. Vaccine 24 (42-43):6503-6512

Ferris, N.P., King, D.P., Reid, S.M., Hutchings, G.H., Shawa, A.E., Paton, D.J., Goris, N., Haas, B., Hoffmann, B., Brocchi, E., Bugnetti, M., Dekker, A., De Clercq, K. 2006. Foot-and-mouth disease virus: A first inter-laboratory comparison trial to evaluate virus isolation and RT-PCR detection methods. Veterinary Microbiology 117(2-4):130-140

Dekker, A., Moonen, P., Pol, J.M.A. 2005. Linear hoof defects in sheep infected with foot-and-mouth disease. Veterinary Record 156; 572-575

Greiner, M., Dekker, A.. 2005. On the surveillance for animal diseases in small herds. Preventive Veterinary Medicine 70; 223–234

Orsel, K., Dekker, A., Bouma, A, Stegeman, J.A., de Jong, M.C.M. 2005. Vaccination against Foot and Mouth Disease reduces virus transmission in groups of calves. Vaccine 23 (41); 4887-4894

Bouma, A., Dekker, A., de Jong, M.C.M. 2004. No foot-and-mouth disease virus transmission between individually housed calves. Veterinary Microbiology 98; 29-36.

Moonen, P., van der Linde, E., Chénard, G., Dekker, A. 2004. Comparable sensitivity and specificity in three commercially available ELISAs to differentiate between cattle infected with or vaccinated against foot-and-mouth disease virus. Veterinary Microbiology 99; 93-101.

Eblé, P.L., Bouma, A., de Bruin, M.G.M., van Hemert-Kluitenberg, F., van Oirschot, J.T., Dekker, A. 2004. Vaccination of pigs two weeks before infection significantly reduces transmission of foot-and-mouth disease virus. Vaccine 22 (11-12); 1372-1378

Moonen, P., Jacobs, L., Crienen, A., Dekker, A. 2004. Detection of carriers of foot-and-mouth disease among vaccinated cattle. Veterinary Microbiology 103; 151-160

Chénard, G., Miedema, K., Moonen, P., Schrijver, R.S., Dekker, A. 2003. A solid-phase blocking ELISA for detection of type O foot-and-mouth disease virus antibodies suitable for mass serology.  Journal of Virological Methods 107 (1); 89-98.

Moonen, P., Boonstra, J., Hakze van der Honing, R., Boonstra- Leendertse, C., Jacobs, L., Dekker, A. 2003. Validation of a LightCycler-based reverse transcription polymerase chain reaction for the detection of foot-and-mouth disease virus. Journal of Virological Methods 113; 35-41.

Tomassen, F. H. M., de Koeijer, A., Mourits, M. C. M., Dekker, A., Bouma, A., Huirne R. B. M. 2002. A decision-tree to optimise control measures during the early stage of a foot-and-mouth disease epidemic, Preventive veterinary medicine 54 (4); 301-324.

Pluimers, F.H., Akkerman, A.M., van der Wal, P., Dekker, A., Bianchi, A. 2002. Lessons from the foot and mouth disease outbreak in the Netherlands in 2001. Revue Scientifique et Technique Office International Des Épizooties 21 (3); 711-721.

Dekker, A., Gijsen, E., 1998. The possible use of native foot-and-mouth disease non-structural protein 3A in a serological screening test. Veterinary Quarterly 20; S27-S28.

Dekker, A. 1998. Inactivation of foot-and-mouth disease virus by heat, formaldehyde, ethylene oxide and g radiation. Veterinary record 143; 168-169.

Chénard, G., Bloemraad, M., Kramps, J.A., Terpstra, C., Dekker, A. 1998. A monoclonal antibody-based ELISA to detect antibodies directed against swine vesicular disease virus. Journal of virological methods 75; 105-112.

Dekker, A., Terpstra, C. 1996. Prevalence of foot-and-mouth disease antibodies in dairy herds in the Netherlands, four years after vaccination. Research in Veterinary science 61; 89-91.

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