The FUSIONS (Food Use for Social Innovation by Optimising Waste Prevention Strategies) Project, funded by the European Union, aims to contribute to a more resource efficient Europe by signficantly reducing food waste. Running for 4 years (2012-2016), FUSIONS has 21 partners from 13 countries, bringing together universities, knowledge institutes, consumer organizations, and businesses on the topic of reducing food waste in the food supply chain from farm to fork. The project has established a European Multi-Stakeholder Platform, currently claiming 140+ members from across the FSC, to help generate a shared vision and strategy to prevent food waste across the FSC and will support achieving a targeted reduction of 50% food waste by 2020 combined with a 20% reduction in food supply chain resource inputs (e.g. water, energy, chemicals, etc.). The FUSIONS project also supports 7 pilot projects to prevent food waste in practice. FUSIONS will deliver a European handbook to quantify and monitor food waste, provide recommendations for effective policy measures from a European and national perspective, and feature innovative approaches to tackle food waste. Food waste is a global issue, and therefore insights from both Europe and other global regions should be shared to encourage new initiatives to address the global sustainability of our food system.