Publicaties

The use of genomics in European livestock genebank collections

Crooijmans, R.P.M.A.; Colli, Licia; Stella, A.; Ajmone-Marsan, P.; Hiemstra, S.J.; Tixier-Boichard, M.

Samenvatting

often in time and overlap between the different versions and platforms is not always guaranteed. Furthermore, in several cases arrays are not freely available without permission of the consortia involved in their development. In the
framework of the Horizon2020 IMAGE project, we have identied a large pool of SNP variants by whole genome sequencing of over 500 individuals from a large variety of local breeds and species and combined this with publicly available SNPs to develop panels to be used for different applications and analyses. One of these applications is the development of a multi- species SNP array (that might include cattle, sheep, goat, pig chicken, turkey, buffalo, horse, duck, rabbit, camel, camelids, honey bee) containing 10k SNPs per species selected from the total SNP pool. This low cost SNP array will make it possible to genotype a large number of samples of the different species collected in gene banks worldwide. Opening the molecular reservoir of variation in these gene bank collections will add value to the material stored, detect the uniqueness of the collections and monitor variation changes over time. The generated whole genome sequences will also be used in genome wide association studies (GWAS) for specic traits present in traditional breeds, like e.g. ptilopody and bantam traits in chicken. The variants related to these and other traits of interest, detected in the course of IMAGE project, or variants presented in literature for specic traits, will also
be selected and added on the multi-species SNP array. The IMAGE project received funding from the EU H2020 Research and Innovation Programme under the grant agreement n° 677353.