Widespread coral reef decline has led to degradations in ecosystem services that coral reef ecosystems provide (e.g., provision of fish, shoreline protection and recreation). Marine resource managers are challenged with establishing strategies that can mitigate or prevent such degradation. Computer models can help shed light on the interactions and synergies of the various disturbances (e.g., fishing, hurricanes, climate change and excess nutrients) that play a role in reef degradation and on the consequences for human users. In this thesis, I explain the development of a coral reef ecosystem model that includes key functional species groups (e.g., herbivores, piscivores, algae, corals, invertebrates) and incorporates the key dynamics that influence a reef ecosystem through a case study for Guam. With the model I then evaluate the ecological and socio-economic tradeoffs of selected management strategies. When the effects of climate change were taken into account, scenarios with improved watershed and some form of fishery regulation performed fairly equally with regard to indicators for the status and resilience of the reef, but none could prevent a collapse in coral biomass by mid-century under a business-as-usual greenhouse gas emission scenario.