Nature provides remarkable examples of function derived from structure, e.g. the ability of the gecko to walk over the ceiling. We developed a novel fabrication method top produce nanopatterned surfaces inspired by nature, using small spheres (Colloids) as template. The effect of these structures on adhesion and wetting was investigated. Our nano PPMS surfaces showed a significant increase in adhesion with respect to a flat control sample, and the contact angle of a water droplet switched from < 90 degrees (hydrophilic) tot > 90 degrees (hydrophobic), due to our structures.