Organisms are affected by factors of the environment within which they live. These factors determine the extent to which they thrive in the environment. Snails responsible for the transmission of schistosomiasis live in water and are subject to physical, chemical and biological status of the aquatic systems they inhabit. Human related factors also play an important role in regulating assemblages of these gastropods and supporting the transmission cycle. While much study has been invested in understanding the effects of environmental factors on Schistosoma host snails and/or the predators, there is little corresponding effort to understand effects of these factors on trophic interactions of these groups of organisms. Our study therefore, focussed on developing an understanding of the predator-prey interactions of Schistosoma host snails and their predators, and the factors affecting these interactions. We envisaged that this would provide for clear linkage of environment and host-predator interaction in the control of Schistosomiasis. This study hinges on the premise that, suppressing populations of host snails through ecological means is both environmentally and socioeconomically sustainable in resource poor communities in sub-Saharan Africa.