Local modification and laser-welding production of functionalized microfluidic chips

Promotie

Local modification and laser-welding production of functionalized microfluidic chips

Promovendus mr. RP (Rui) Rijo da Costa Carvalho MSc
Promotor prof.dr. JT (Han) Zuilhof
Copromotor dr. SP (Sidharam) Pujari PhD
Copromotor dr EX Vrouwe
Organisatie Wageningen University & Research, Laboratory for Organic Chemistry
Datum

ma 3 juli 2017 16:00 tot 17:30

Locatie Auditorium, building number 362
Generaal Foulkesweg 1
362
6703 BG Wageningen
0317-483592

Summary


The ability to locally functionalize the surface of glass and polymers allows for myriad biomedical and chemical applications. When we started this research in 2015, enclosed surfaces such as microfluidic channels were not easily amenable to localized functionalization. Furthermore, pre-functionalization of microfluidic devices was incompatible with the typical high-temperature substrate bonding procedures. The work described in this thesis successfully tackled these issues. We showed how light can be used to pattern DNA onto enclosed glass. Additionally, this thesis shows how typically considered “inert” plastics can be quickly modified in water at room temperature. Finally, laser-based technologies were used to study the low-temperature fabrication of micro-devices.