Title Thesis: Worms under stress: unravelling genetic complex traits through perturbation
Despite of its simplicity, the tiny nematode Caenorhabditis elegans already occupies for decades an important place in the “science walk of fame” since it became the first organism which genome was completely sequenced in 1998.
Moreover the different experiments and findings that this worm has been contributing over the last years are numerous. One of its most noticeable usages as a human genetics model organism, places it directly on the top of biomedicine research. My thesis not only highlights the benefits of using this model but also introduces new techniques and interesting novel findings, which point to be of a great relevance for the current complex human genetics research.