PhD defence Miriam Rodriguez Sanchez

Title Thesis: Worms under stress: unravelling genetic complex traits through perturbation

Promovendus Miriam Rodriguez
Promotor J (Jaap) Bakker
Copromotor JE (Jan) Kammenga
Organisatie Laboratory of Nematology

vr 14 maart 2014 11:00 tot 12:30

Locatie Auditorium, building number 362
Generaal Foulkesweg 1
6703 BG Wageningen


Despite of its simplicity, the tiny nematode Caenorhabditis elegans already occupies for decades an important place in the “science walk of fame” since it became the first organism which genome was completely sequenced in 1998.

Identification and characterization of genes involved in stress response in C. elegans both represent an excellent starter to study complex human diseases.
Miriam Rodriguez Sanchez

Moreover the different experiments and findings that this worm has been contributing over the last years are numerous. One of its most noticeable usages as a human genetics model organism, places it directly on the top of biomedicine research. My thesis not only highlights the benefits of using this model but also introduces new techniques and interesting novel findings, which point to be of a great relevance for the current complex human genetics research.