Rabies is a zoonotic disease that causes 60.000 human deaths worldwide per year. Since its introduction in Flores Island, Indonesia, rabies has been posing a serious public health threat on the island with significant economic consequences. To control the disease, annual dog vaccination campaigns have been implemented to vaccinate all dogs free of any charge. Nevertheless, these campaigns have not been successful in eliminating rabies from the island.
The main objective of this dissertation was to support future decisions on the control of rabies in Flores Island by providing insight into the role of socio-demographic and psychological factors of dog owners in the uptake of rabies control measures and by analyzing the cost-effectiveness of alternative vaccination strategies. Results indicated that control of rabies by mass dog vaccination can be cost-effective in reducing human rabies cases as long as the campaigns are adjusted to the situation-specific circumstances of the dog owners.