TWIN-SHIME: the Simulator of Human Intestinal Microbial Ecosystem explained

Seminar

TWIN-SHIME: the Simulator of Human Intestinal Microbial Ecosystem explained

The Simulator of Human Intestinal Microbial Ecosystem (SHIME®) is a dynamic in vitro simulation platform for digestion of food. This research facility offers opportunities for research fields as, e.g., microbiology, food safety, digestion, product design, food chemistry and human and animal nutrition.

Organisator Shared Research Facilities and Food Quality and Design
Datum

di 14 maart 2017 12:00 tot 13:15

Locatie Impulse, building number 115
Stippeneng 2
115
6708 WE Wageningen
+31 317-482828

A seminar organized by Shared Research Facilities and Food Quality and Design will highlight the opportunities of this research device. The developer and manufacturer ProDigest will outline the research possibilities of the SHIME® technology platform. Wageningen University PhD student Jonna Koper will explain her research using the newly acquired TWIN-SHIME. After the presentations there will be ample opportunity for questions and meeting the experts and fellow researchers.

Twin-Shime

The SHIME® platform, a succession of five reactors, each imitating a different segment of the human gastrointestinal tract and the colon, can provide detailed information of the fermentation profile. Two parallel running reactors (TWIN) make it possible to study e.g., probiotic effects of selected microorganisms, prebiotic effects of selected food ingredients or foods, shift in gut microbiota upon different dietary patterns or antibiotic treatment, bioavailability of micronutrients and macronutrients, and the kinetics of nutrients and phytochemical metabolism by the gut microbiota.

Interested what the TWIN-SHIME in vitro simulation can offer your research? Please be welcome to attend the free seminar. Coffee and tea will be served and please bring your own lunch.

Programme
12:00 - 12:05 Introduction by Shared Research Facilities
12:05 - 12:35 Pieter Van den Abbeele (ProDigest): An advanced in vitro technology platform to study the mechanism of action of bioactives in the gastrointestinal tract
12:35 - 12:45 Jonna Koper (WUR): AhR activation during in vitro fermentation of oregano using SHIME®
12:45 - 13:15 Questions and discussion