Wageningen Bioveterinary Research (WBVR) is researching the best laboratory-based methods of identifying bacteria that are resistant to certain groups of antibiotics.The objective is to find an optimal method which can then be used in the future to cultivate resistant bacteria in a uniform way in human, veterinary and food laboratories.
When infections in humans are caused by bacteria that are resistant to antibiotics, treatment is more difficult. As part of the IMPART (IMproving Phenotypic Antimicrobial Resistance Testing) project, WBVR is working with European partners to research the optimal cultivation method for identifying such bacteria. The project is part of the One Health European Joint Programme (EJP).
Identifying resistant bacteria
The researchers use meat and dung samples from livestock to research different cultivation methods. These samples have been artificially contaminated with a small quantity of bacteria in the ANSES laboratory in Fougères, France. The bacteria are strains of E. coli, Klebsiella or Salmonella that are resistant to carbapenems or colistine. These antibiotics are very important in treating humans infected with resistant bacteria. From the perspective of One Health, it’s important to develop methods suitable for humans, animals and food, in order to better understand the spread of such bacteria and how to prevent it.
The first round of this research is a pilot and was carried out in December 2018 by three laboratories: Netherlands National Institute for Public Health and the Environment, Wageningen Bioveterinary Research and The Norwegian Veterinarian Institute in Oslo. In 2019, the research will be replicated on a larger scale together with ten European partners.