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Great interest in new mass spectrometry facilities

Gepubliceerd op
20 juni 2014

The lunch seminar “Applications of advanced mass spectrometry @ Wageningen UR” on Wednesday 18 June in Impulse attracted over 95 researchers. The seminar gave an overview of all mass spectrometry technologies offered by CAT-AgroFood and their applications. Five of them have been recently invested and provide researchers from Wageningen UR and from other organisations new possibilities for their research.

The lunch seminar “Applications of advanced mass spectrometry @ Wageningen UR” on Wednesday 18 June in Impulse attracted over 95 researchers. The seminar gave an overview of all mass spectrometry technologies offered by CAT-AgroFood and their applications. Five of them have been recently invested and provide researchers from Wageningen UR and from other organisations new possibilities for their research.

After the introduction by Petra Caessens, manager operations of CAT-AgroFood, pitches were held by the mass spectrometry experts.

Edwin Bakx presented the applications of MALDI-TOF/TOF MS, preparative LC-MS and the new UPLC-ESI-TWIM-MS (Synapt-G2Si). He showed that the latter instrument is very useful for the identification of isomeric compounds in complex samples, and for the determination of chemical modifications of proteins.

Michel Nielen and Desalegn Etalo showed how ambient mass spectrometry imaging can be used as a tool for imaging where specific molecules are located on surfaces. They showed examples of imaging compounds as among which pesticides on food and plants.

The pitch of Twan America showed that the UPLC-triple quad MS/MS is a good and fast technology for accurate and sensitive detection and quantification of small biomolecules, such as metabolites and peptides.

Ric de Vos showed the applications of the new Q Exactive Orbitrap. One of its key features is that it has a ultra-high mass resolution (very sharp mass peaks are recorded), which can be used for the determination of the elemental formula of compounds. Another key feature is that it can produce accurate masses of positive and negative ions (polarity switching) in a single run. This makes it suitable for applications in compound identification and targeted and untargeted analysis in metabolomics and proteomics research.

Francel Verstappen presented the high-throughput headspace sampling chamber, that is designed to collect volatiles in controlled and adjustable light, temperature, CO2 and humidity conditions. The volatiles, even ultra-low concentrations or of unknown identity, can subsequently be analysed accurately with the new GCxGC-QTOF mass spectrometer.

The seminar was concluded with an information market where the participants had the opportunity to discuss their specific questions with the experts. If you are interested to know more about the facilities, please contact us.