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Publication: Monomeric IgA can be produced in planta as efficient as IgG, yet receives different N-glycans

Gepubliceerd op
29 september 2014

"As the IgA isotype offers unique features for monoclonal antibody based therapies we made a comparative analysis of the plant-based production of several antibodies on either an IgG1 or IgA1 backbone. Surprisingly little variation in yield was found, but IgA receives different N-glycans compared to IgG when expressed in planta."