Publication in ‘Cell Host and Microbes’: Conserved Fever Pathways across Vertebrates: A Herpesvirus Expressed Decoy TNF-α Receptor Delays Behavioral Fever in Fish

Gepubliceerd op
10 februari 2017

In this article we show that fish can show a so-called ‘behavioural fever’ during a viral infection and that the mechanisms behind such behaviour are very conserved between fish and humans.

When we (warm blooded animals) get infected by a Virus we are all familiar with the fever symptoms, and we know that increasing the body temperature will reduce virus growth.

Fish cannot change their body temperature but we describe how fish move towards higher temperatures (behavioural fever), what is the mechanism behind this behaviour and how such behaviour is very effective in stopping viral replication. Most importantly we discovered a virus molecule that is able to interfere with such a mechanism.  

Read her the full article.

Click here for a press release and an article in Nemo Kennislink (in Dutch)

and also the article in the Resource (with video)