Various population based studies have shown associations between higher BMI and lower iron status and anaemia. We have shown this for example for Mexican women and children. It may well be that this is due to lower iron absorption induced by inflammatory processes.
In this project, we firstly assess iron absorption over a range of BMI’s. In addition, we compare the enhancing effect of ascorbic acid on iron absorption between BMI groups. Secondly, we assess iron absorption in obese subjects before and after weight loss through bariatric surgery. This study takes place in collaboration with the University of Monterrey in Mexico. With this, we aim to better understand the underlying processes that explain lower iron status in relation to obesity.
The effects of fat loss after bariatric surgery on inflammation, serum hepcidin, and iron absorption
American Journal of Clinical Nutrition 104 (2016)4. - ISSN 0002-9165 - p. 1030 - 1038.
In overweight and obese women, dietary iron absorption is reduced and the enhancement of iron absorption by ascorbic acid is one-half that in normal-weight women
American Journal of Clinical Nutrition 102 (2015)6. - ISSN 0002-9165 - p. 1389 - 1397.
Sharply higher rates of iron deficiency in obese Mexican women and children are predicted by obesity-related inflammation rather than by differences in dietary iron intake
American Journal of Clinical Nutrition 93 (2011)5. - ISSN 0002-9165 - p. 975 - 983.
Does Obesity Increase Risk for Iron Deficiency? A Review of the Literature and the Potential Mechanisms
International Journal for Vitamin and Nutrition Research 80 (2010)45. - ISSN 0300-9831 - p. 263 - 270.
More research: International nutrition