An increasing number of people in the world suffer from hyperimmune diseases (e.g. allergy, diabetes, multiple sclerosis).
The most widely used therapies are currently based on treatment with drugs knwon for their extraordinary side-effects. Our lab at the moment is looking into the possible treatment of these hyperimmune diseases with parasitic worms.
This program is inspired by the observations of worm capble of suppressing hyperimmune activities. People carrying worms infections are at a significantly lower risk of developing a hyperimmune condition. We want to understand the mechanism behind this immunomodulation of a host by a worm.