On February 20th the Wageningen Centre for Systems Biology (WCSB) will organise a seminar on systems biology. The seminar is free, will take an hour and will be followed by drinks. No registration is necessary, so feel free to come by!
Dr Ramon Grima, Associate Professor, University of Edinburgh and member of the Centre for Systems and Synthetic Biology (SynthSys)
"The importance of noise in biochemical dynamics"
In this talk, Ramon will review the present day understanding of how noise affects the kinetics of biochemical pathways. He will use examples to show how in some instances noise is a nuisance and hence the need of reducing it whilst in other circumstances noise can be exploited or harnessed for example to produce concentration oscillations. He will also present an introduction to the mathematical and simulation frameworks used to probe the role of noise and how this differs from the traditional framework of ordinary differential equations commonly used in physical chemistry and systems biology. Discussed will be the merits and disadvantages of commonly used software and mathematical approaches to study noise and showcase new tools developed in his group which overcome these disadvantages and which hence enable more realistic simulation of large scale noisy pathways.
Ramon Grima got a PhD in physics from Arizona State University (USA). After postdocs in Indiana University and Imperial College London, he became a lecturer (Assistant Prof) at the School of Biological Sciences at the University of Edinburgh. Presently he is a Reader (Associate Professor) at the University of Edinburgh and member of the Centre for Systems and Synthetic Biology (SynthSys).
More information about WCSB and the 14 different projects can be found on the website www.wur.nl/systemsbiology.