Understanding of the Self- and Co-Assembly Behavior of Recombinant Protein Polymers

This thesis highlights current progress in the development of protein-based polymers that form hydrogels, their application potential, and advantages of these materials over other biomaterials.

Promovendus MD (Monika) Golinska MSc
Promotor prof.dr. MA (Martien) Cohen Stuart
Copromotor dr. RJ (Renko) de Vries
dr. FA (Frits) de Wolf
Organisatie Physical Chemistry and Soft Matter

di 7 januari 2014 16:00 tot 17:30

Locatie Auditorium, building number 362
Generaal Foulkesweg 1
6703 BG Wageningen
A powerful tool in the design of new recombinant polypeptides could be the incorporation of sequences that allow for site-specific crosslinking using enzymes such as transglutaminase
Monika Dominika Golińska

A key part of the growing field of biomedical sciences deals with the development of new, controlled and biocompatible biomaterials. In the thesis we present results on the design, production, purification and characterization of stimuli responsive protein polymers that could ultimately be used in that field. Protein-polymers are composed of two or three blocks that are able to self- and co-assemble. An important theme in the thesis is to highlight the specific advantages of our new protein polymer for future biomedical applications.