Friedemann Weber

Friedemann Weber received his PhD in biology in 1997 after his studies in the group of professor Otto Haller at the University of Freiburg. Between 1998 and 2000 he worked as a post-doc at the University of Glasgow in the laboratory of Prof. Richard Elliott, where he started his research on bunyavirus interferon antagonism.

Induction and suppression of the interferon response by bunyaviruses

In the year 2000, he was appointed group leader at the Department of Virology at the University of Freiburg where he continued his work on bunyaviruses and expanded his studies with the SARS and MERS coronaviruses. He completed his Habilitation in Virology in 2004 and became assistant professor in 2008. In 2010, he moved to the Philipps University in Marburg, Germany, where he still holds his position as associate professor. His research is aimed at (i) understanding the mechanisms of virus recognition by the host cell and the upregulation of IFN synthesis, (ii) the host-encoded IFN-induced proteins responsible for the antiviral effect against SARS-CoV and bunyaviruses, and (iii) identifying and characterizing viral proteins with anti-IFN activity. The studies performed by the group of Prof. Weber have led to the identification of viral key structures that trigger the induction of IFNs, and to the elucidation of viral mechanisms of pathogenesis. His research is published in prestigious journals including Journal of Virology, Journal of Biological Chemistry, Cell Host & Microbe and Science.