Studentenverhaal

New Testimonial Aafke Aartse

As Molecular Life Scientist, I did my Master Thesis at the Laboratory of Nematology. I was busy in the lab for six months and I worked with the nematode Caenorhabditis elegans under the supervision of Jan Kammenga and Miriam Rodriguez.

In this research field are Recombinant Inbred Lines (RILs) and Introgression Lines (ILs) often used, to connect natural variation with genetic variation of two most diverse strains of C. elegans
Aafke Aartse

August 2012

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C. elegans is used as a model organism in several researches, for example research in cancer pathways, ageing, and immunity in human. Also, the nematode is used in natural and genetic variation research. In this research field are Recombinant Inbred Lines (RILs) and Introgression Lines (ILs) often used, to connect natural variation with genetic variation of two most diverse strains of C. elegans. My thesis subject was based on this type of research. I generated a subset of ILs in C. elegans by crossing the wild type strain with an IL which has a remarkable phenotype in heat-shock recovery. After the crossing I checked the genotype of all those sub-ILs. It was a lot of work, but that didn’t bother me and I had a lot of fun working in the lab. Also, because of the friendly and helpful people, the coffee breaks with a lot of pie and fun, and the informative and motivating meetings, I had a great time at the department of Nematology!

Oh, and of course, thanks for the huge chocolate soccer cup! Which I won because in my opinion, Sweden was the winner of EK 2012!