Over the last months I have been working at the Laboratory of Nematology in the Laboratory of Molecular Recognition and Antibody Technology group (LMA) as an Erasmus student. During this time I realized my BSc thesis project, which concerned production of Immunoglobulin A (IgA) in transgenic tobacco plants.
IgA is the most abundant antibody isotype in human secretions and has an immunotherapeutic potential which makes it a promising treatment for (auto)immune diseases. In my project we focused on assessing the yield and quality of recombinant IgA, which was produced in Nicotiana benthamiana. I have been working under the supervision of Lotte Westerhof and Arjen Schots. At the beginning I had little lab experience but over time I have mastered many useful techniques and was able to work independently. Also, during the weekly LMA literature or work discussions I gained a lot of theoretical knowledge and learnt how to interpret my results and draw conclusions. The experience I got at the Nematology Department made my further education much easier. It was a pleasure to work as a member of this group, not only because of an advanced research topic, The people working there are really helpful and enthusiastic and create a fun-filled, friendly atmosphere. In general, I couldn’t choose a better place for doing my BSc thesis.