As I am a third year biology student, who is mainly interested in the medical aspect of biology, I chose to do my Bsc-thesis within the Nematology group (at the Laboratory of Molecular Recognition and Antibody Technology (LMA)). For three months, I worked there on the effects of mushroom compounds on dendritic cells. Arjen Schots was my supervisor during this period.
During my time at Nematology I learned a lot, not only did I learn about immunology, but I also gained a better understanding of what working in a lab is like. I was greatly supervised in the lab by Ruud Wilbers. I stimulated dendritic cells with certain mushroom extracts (β-glucan extracts and fresh ground extracts) and investigated the response of the dendritic cells. I did this by measuring their cytokine production by ELISA; and by measuring upregulation of certain cell surface markers by flow cytometry. I found that many of the extracts indeed induced cytokine production and upregulation of certain markers. This indicated that mushrooms induce maturation of the dendritic cells and that the dendritic cells in turn have an increased capacity to activate the adaptive immune system. So these were interesting results! The atmosphere was always great in the lab and everyone was willing to help you when needed.
So I can honestly advice everyone to do their thesis at Nematology. You get great supervision, there are good supplies and above all there is a great atmosphere!