For my MSc thesis project, I did my research about phenotypic plasticity in the nematode Caenorhabditis elegans, also common as a model organism in the genetic studies. I evaluated the genetic architecture of four wild type strains as well as analyzed and measured the genetic and phenotypic variations.
My research project was part of the NEMADAPT project supervised by Jan Kammenga, Basten Snoek and Rita Volkers. I have been analyzing quantitative trait loci, a large genomic region containing many genes associated with their genotype-environment interactions, once parental and recombinant inbred lines were exposed to the stress conditions such as heat treatment. A cross between novel wild type strains enabled higher genetic diversity between those lines and also provided a recombinant inbred population. As part of my project, I have done genotyping of parental and recombinant lines with SNPs markers as well as phenotyping of the same lines by heat treatment. As a result, I observed genetic and phenotypic variations between lines and also detected QTL on the X chromosome.
The working atmosphere is truly very nice and everyone is willing to help. It was a real pleasure to spend working hours in laboratory. My research days were very nice and unforgettable at Nematology Department. I gained a lot of experience and learned many new things about C. elegans. I will always remember nice moments during my stay and work in Wageningen