Studentenverhaal

Testimonial Irina Ćalić

For my MSc thesis project, I did my research about phenotypic plasticity in the nematode Caenorhabditis elegans, also common as a model organism in the genetic studies. I evaluated the genetic architecture of four wild type strains as well as analyzed and measured the genetic and phenotypic variations.

I have done genotyping of parental and recombinant lines with SNPs markers as well as phenotyping of the same lines by heat treatment
Irina Ćalić

June 2011

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My research project was part of the  NEMADAPT project supervised by Jan Kammenga, Basten Snoek and Rita Volkers. I have been analyzing quantitative trait loci, a large genomic region containing many genes associated with their genotype-environment interactions, once parental and recombinant inbred lines were exposed to the stress conditions such as heat treatment. A cross between novel wild type strains enabled higher genetic diversity between those lines and also provided a recombinant inbred population. As part of my project, I have done genotyping of parental and recombinant lines with SNPs markers as well as phenotyping of the same lines by heat treatment. As a result, I observed genetic and phenotypic variations between lines and also detected QTL on the X chromosome.

The working atmosphere is truly very nice and everyone is willing to help. It was a real pleasure to spend working hours in laboratory. My research days were very nice and unforgettable at Nematology Department. I gained a lot of experience and learned many new things about C. elegans. I will always remember nice moments during my stay and work in Wageningen