Studentenverhaal

Testimonial Marloes van Adrichem

For my bachelor thesis I wanted to find a topic that was both related to biotechnology and plants. At the Laboratory of Nematology I got the opportunity to combine these two fields.

It was really interesting to see how the process of producing proteins in plants can be done
Marloes van Adrichem

May 2015

Student Marloes van Adrichem.png

The aim of my thesis was to produce a human protein -Transforming Growth Factor β1 (TGF-β1) – in a tobacco plant. First the TGF-β1 gene was amplified by PCR using a human genome as template. The gene was inserted into a plasmid, which was then inserted into the plant by using modified bacteria. I tested if the plants produced the protein and additionally did a biological activity test. It was really interesting to see how the process of producing proteins in plants can be done. And to make it even better; the produced TGF-β1 was biologically active for the first time after experimenting for almost 8 years! I learned a lot, was happy with the results and staff members were nice and helpful . Altogether it made my time at the Nematology department unforgettable.