To complete my master Biotechnology, I had the honour to do my thesis in the laboratory of Nematology on a novel field within glyco-engineering. Under the supervision of Ruud, I tried to identify novel glycosyyltransferase genes in C. elegans.
Since several nematode glycans have known immunomodulatory properties, it would be interesting to know which genes are involved in the glycan synthesis. By performing RNAi and CRISPR-cas9 in C. elegans I was able to gain more information about these novel glycosyltransferase genes.
During my master thesis, I received a lot of freedom to choose my own topic and perform my own experiments. I chose this topic because the lack of knowledge in this field and the ability to combine glyco-engineering with C. elegans work. During my thesis I performed a wide variety of experiments, which gained me a lot of new experiences in lab work. This will be very useful during my internship and in my future job.
Besides the freedom, the working atmosphere of the department is relaxed. Everyone is open and willing to help you out. This makes the collaboration between students and student and supervisor a relaxed and pleasant experience. I would recommend to do your thesis in the laboratory of Nematology if you want to combine gaining new experiences and having a nice time with your fellow students and supervisors.